PRE is responsible for addressing the evolving needs of the three Agencies in promoting the ethics of research involving humans. It functions as an interdisciplinary and pluralistic advisory body, providing the Agencies with independent reflection and advice on human research ethics, consistent with the Tri-Council Policy Statement: Ethical Conduct of Research Involving Humans, 2nd edition (TCPS 2).
PRE’s mandate is to:
In carrying out its mandate, PRE is committed to openness and transparency.
PRE has 12 members. In addition, the Executive Director of the Secretariat and a representative from CIHR's Stem Cell Oversight Committee are ex officio members without voting rights. Observers may also be invited to participate in the meetings.
In addition to geographical and gender representation, PRE membership provides:
All members are volunteers. They do not receive honoraria in compensation for their contribution of expertise and time, though the Secretariat covers their expenses (such as travel and accommodation).
The Presidents of the three Agencies appoint PRE members. Initial appointments are for a period of three years, with the possibility of extension for one to three years for a maximum total of six years. The appointments are staggered to provide flexibility and continuity.
PRE’s Chair is also appointed by the three Presidents. The initial term of appointment is for two years with the possibility of one or more extensions.
PRE will usually meet at least once each year, communicating further in person or by teleconference as required. The Executive Director and staff of the Secretariat participate in the meetings.
A majority of its members (50% plus 1), which must include the Chair, or his/her designate.
PRE reports to the Presidents of the Agencies, providing recommendations regarding the TCPS 2. The Presidents then determine the appropriate action to be taken. The Panel Chair reports annually on PRE's activities to each of the Agencies' Councils.
Tri-Council Policy Statement: Ethical Conduct of Research Involving Humans, 2nd edition (2010)